Motif ID: FOX{D1,D2}.p2

Z-value: 1.213


Transcription factors associated with FOX{D1,D2}.p2:

Gene SymbolEntrez IDGene Name
FOXD1 2297 forkhead box D1
FOXD2 2306 forkhead box D2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXD1chr5_-_72744351-0.193.1e-01Click!
FOXD2chr1_+_47901688-0.096.3e-01Click!


Activity profile for motif FOX{D1,D2}.p2.

activity profile for motif FOX{D1,D2}.p2


Sorted Z-values histogram for motif FOX{D1,D2}.p2

Sorted Z-values for motif FOX{D1,D2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{D1,D2}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_71551564 4.749 TSPAN8
tetraspanin 8
chr1_-_161337663 3.877 NM_001013625
 C1orf192
chromosome 1 open reading frame 192
chr12_-_71551778 3.703 NM_004616
 TSPAN8
tetraspanin 8
chr11_+_73359734 3.304 NM_001130036
 PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr4_+_70861647 2.760 NM_001009181
NM_003154
 STATH

statherin

chr10_+_51549552 2.724 NM_002443
NM_138634
 MSMB

microseminoprotein, beta-

chr5_+_78531848 2.669 NM_152405
 JMY
junction mediating and regulatory protein, p53 cofactor
chr17_+_58755158 2.618 NM_001099432
NM_017679
 BCAS3

breast carcinoma amplified sequence 3

chr14_+_56585147 2.464 PELI2
pellino homolog 2 (Drosophila)
chr14_+_56584854 2.431 NM_021255
 PELI2
pellino homolog 2 (Drosophila)
chr6_+_135502521 2.235 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr17_+_9745847 2.082 GLP2R
glucagon-like peptide 2 receptor
chr9_-_3223007 1.861


chr1_+_151630710 1.860 SNX27
sorting nexin family member 27
chr6_+_135502445 1.856 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
 MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr6_+_135502477 1.833 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr3_+_113616317 1.819 NM_001172105
 GRAMD1C
GRAM domain containing 1C
chr7_-_95225802 1.782 NM_002612
 PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr10_+_95848811 1.759 NM_001165979
 PLCE1
phospholipase C, epsilon 1
chr1_+_227127959 1.746 ADCK3
aarF domain containing kinase 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
2.53 4.46e-02 GO:0032582 negative regulation of gene-specific transcription
2.29 4.97e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.02 2.26e-03 GO:0045892 negative regulation of transcription, DNA-dependent
2.01 2.21e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
2.00 4.92e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.98 2.08e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.98 4.19e-03 GO:0051253 negative regulation of RNA metabolic process
1.97 2.07e-04 GO:0009890 negative regulation of biosynthetic process
1.93 3.63e-03 GO:0010629 negative regulation of gene expression
1.91 5.73e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.88 8.45e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.72 2.48e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.71 1.00e-02 GO:0031324 negative regulation of cellular metabolic process
1.64 4.95e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.63 3.81e-02 GO:0009892 negative regulation of metabolic process

Nothing significant found in compartment category.

Nothing significant found in function category.